I recommend using a standardized rhodiola rosea extract (3% rosalins, 1% salidroside) at 200-400mg, taken 30 minutes before the start of each shift on an empty stomach. For a nurse working rotating 12-hour shifts, I've seen success with taking 300mg at 6:30am for day shifts or 6:30pm for night shifts - this timing ensures the adaptogenic benefits kick in during peak stress hours while allowing the body to naturally wind down 8-10 hours later when it's time to sleep.