Founder & Medical Director at New York Cosmetic Skin & Laser Surgery Center
Answered 3 months ago
Male patients ask about nitric oxide supplements for circulation and erections. L citrulline can raise L arginine and nitric oxide. Beetroot nitrate can also raise nitric oxide. Pine bark and hawthorn are marketed for vascular tone, not instant results. In 2025, a pine bark extract meta analysis of 27 randomized trials (1,685 participants) found mean systolic blood pressure lower by 2.26 mmHg and diastolic lower by 2.62 mmHg, with LDL lower by 5.07 mg/dL. A 2025 hawthorn meta analysis reported systolic blood pressure lower by 6.65 mmHg. Side effects are usually stomach upset, headache, and low blood pressure. Be cautious with antihypertensives, nitrates, and PDE5 drugs. I loop in urology or cardiology colleagues to review your meds and goals.